Material Safety Data Sheet on caffeine exposure: Hallucinations, nervousness, psychosis
While the FDA labels caffeine as GRAS (”Generally Regarded As Safe”), chemical manufacturers are required by law to label caffeine “potentially fatal if inhaled, swallowed or absorbed through the skin” when handling and transporting it. Following is an excerpt from one Material Data Safety Sheet, courtesy of the University of California:
CAFFEINE:
TOXIC.
ACUTE EXPOSURE- Ingestion of large amounts may result in headache, lightheadedness, dizziness, chills, fever, excitement, restlessness, nervousness, insomnia, mild delirium, hallucinations, tinnitus, constricted pupils, decreased visual fields, amblyopia,diplopia, photophobia, and scintillating scotoma. Neurologic symptoms may persist for several days….Other effects may include alternating states of consciousness and muscle twitching, tremors, hyperesthesia, hypertonicity or hypotonicity, trismus, opisthotonus and convulsions. Seizures generally precede death.
CHRONIC EXPOSURE- In addition to the effects detailed in acute exposure, agitation, disturbed sleep, caffeine-induced psychosis, heartburn and hyperventilation may occur. Prolonged use of high doses may result in tolerence, physical and psychological dependence. Symptoms of withdrawal may occur following abrupt cessation.
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